6-APB, 6-(2-Aminopropyl)benzofuran (also known as 6-APB and “Benzofury”) is a novel entactogen substance of the benzofuran class. Its characteristic effects include anxiety suppression, disinhibition, muscle relaxation, and euphoria. It is structurally related to entactogens like MDA, MDMA, 5-APB, and 5-MAPB.
6-APB was first synthesized in 1993 by David E. Nichols as a potential non-neurotoxic alternative to MDMA.However, it did not come into popular recreational use until over a decade later, where it briefly entered the rave scene and global research chemicals market. It was sold along with other novel benzofuran entactogens under the name “Benzofury” before its sale and import were subsequently banned.
Very little data exists about the pharmacological properties, metabolism, and toxicity of 6-APB, and it has only a brief history of human usage. It has been marketed alongside research chemical entactogens like 5-MAPB and 5-APB as a legal, grey-market alternative to MDMA, and is typically commercially distributed by online research chemical vendors. It is highly advised to use harm reduction practices if using this substance
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5 – APB with standard analytic methods. Little is known about the pharmacological or toxicologicale differences between the two, if any.
6 – APB is an analoguee of the class A drug MDA and has similar effects to MDMA Ecstasy.
The name comes from the benzofurans ring in the chemical structure and should not be confused with benzodiazepiness, which are minor tranquillisers
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